We are experiencing an interesting issue when setting up multiple
organizations in MS CRM 4.0 with the Outlook Client. If you are in the
<default> instance everything is fine, BUT if you are in another
organization you can not setup the outlook client. The only way that
we have found to accomplish this is to have the user in the <default>
organization and the disable them and have them in their organization
then everything works.

Does anyone have any ideas on this topic?

Thanks.